产品货号：
Z38721
中文名称：
Hu CD105/Endoglin/ENG Purified抗体
英文名称：
Anti-Hu CD105/Endoglin/ENG Purified Antibody (Clone#MEM-229)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu CD105/Endoglin/ENG Purified Antibody (Clone#MEM-229) |
| 指标别名 | CD105;END;Endoglin;ENG;HHT1;ORW;ORW1 |
| 克隆性 | Monoclonal |
| 检验物种 | pig,human |
| 应用范围 | FCM,WB,IHC-F,ICC |
| 基因名称 | ENG |
| 克隆号 | MEM-229 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.The antibody MEM-229 recognizes an extracellular epitope of CD105 (Endoglin),a 90kDa type I integral membrane homodimer glycoprotein expressed on vascular endothelial cells (small and large vessels),activated monocytes and tissue macrophages,stromal cells of certain tissues including bone marrow,pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow;it is also present on syncytiotrophoblast on placenta throughout pregnancy. |
| 计算分子量 | 71kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD105 (endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3.CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing,infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia.CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration.Normal cellular levels of CD105 are required for formation of new blood vessels. |
| Uniprot ID | P17813 |
| 基因名全称 | Endoglin |
| 蛋白名全称 | Endoglin |
| 推荐稀释比 | Flow cytometry:2～6μg/mL;positive control:Kg1 human acute myelogenous leukemia cell line. Immunohistochemistry (frozen sections):1:200,acetone fixation. Western blotting:Non-reducing conditions. |
相关搜索：Hu CD105/Endoglin/ENG Purified抗体，Hu CD105抗体，Endoglin抗体，ENG Purified单抗